I have also had this issue with my Acer Extensa 5420 Laptop.
It is running an ATI Xpress 1250. It is on the best buy website right now on sale for 499.
The screen will black out while working/clicking and I am forced to do a hard shutdown (no other possible way to get the display working). The PC is still running but the display is just gone. It doesnt loose power since the backlight is still on so it isn't an issue with the LCD display, probably with the motherboard or ATI graphics. Everything is fine when i start up again but this causes me to lose work and settings. I called best buy and they had not heard of this issue with the Acer laptops. Has happened twice and I just purchased this laptop yesterday.
I disabled hibernation and installed all updates including the optional ones. If this keeps happening I will probably try and get this laptop replaced under warranty. It is most likely a hardware issue.