Can I go straight from 10.7.5 to 10.9.3?

Never did bother to go to 10.8 so any issues I should be aware of
jumping from 10.7.5 to 10.9.3? I do have a bootable clone of my current
HD on an external drive done with CCC.

 

Answering the question in the subject: yes, assuming your Mac is
supported by 10.9. Some Macs able to run 10.7 can't upgrade any further:
Late 2006 iMac and MacBook Pro, Mid 2007 Mac Mini, original (early 2008)
MacBook Air, polycarbonate MacBook models prior to early 2009, Mac Pro
prior to early 2008, Xserve prior to early 2009.

It is possible to upgrade directly to 10.9 from any of 10.6.8, 10.7.x or
10.8.x.

You will already have the minimum amount of memory required (2 GB) since
that requirement didn't change between 10.7 and 10.9. In theory, 10.9
should perform somewhat better than 10.7 in low memory conditions, due
to using in-memory compression before it resorts to swapping memory to
disk. Despite this, I recommending 4 GB as a more reasonable minimum
amount of memory for 10.9, and those running memory heavy software (e.g.
Photoshop, virtual machines) will almost certainly need more than that.

As you are already on 10.7, you are past the point where most of the
application compatibility problems occur (PowerPC applications and lack
of Rosetta in 10.7 or later).

There are some obscure system components removed in 10.9, notably Open
Transport networking, which stopped MT-Newswatcher working, but very few
other applications were affected by that one.

In general terms, some applications have needed updates to fix issues
running on 10.9, so you should make sure you've installed any free
updates, and check with the developer for any important apps you use
which may need a paid upgrade to officially support 10.9.

http://roaringapps.com may be a helpful resource, with user-supplied
comments about application compatibility with each of 10.7 and later.

10.9.3 reinstates iTunes direct syncing of contacts/calendars with iOS
devices, which was one of the annoyances for some people with 10.9 to
10.9.2. It hasn't restored copying of contacts and calendars to non-iOS
iPods.

If you have non-Apple devices which currently sync using something like
Missing Sync, they probably still can't sync in 10.9.3.

I haven't seen enough information yet about exactly what Apple restored
in 10.9.3 to get iTunes sync with iOS devices working again, but the
reason it stopped working in 10.9 to 10.9.2 was that Apple had dropped
Sync Services, which other applications like Missing Sync were using to
access the contacts and calendars.

Mark/Space haven't updated their incompatibility warning since 10.9.3
was released, or said anything about it on their blog, but perhaps they
just haven't finshed testing yet, or perhaps Sync Services has only been
partly restored (only working with iTunes).

 

Thank you. I should've made my post a little more complete. I have a
mid-2011 Mac Book Air with 4GB memory. I use the current version of
Thoth (paid) and I know that is compatible. The reason I hadn't
upgraded before was the inability to sync iOS devices via USB, but
that's been reinstated with this version. I've already upgraded iTunes
so that's good to go.